产品货号：
Z34133
中文名称：
SOCS3抗体
英文名称：
Anti-SOCS3 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SOCS3 Antibody |
| 指标别名 | ATOD4;CIS 3;CIS3;Cish3;SOCS 3;SOCS3;SOCS-3;SSI 3;SSI3;STAT induced STAT inhibitor 3 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | SOCS3 |
| 抗体来源 | Mouse |
| 免疫原 | Purified recombinant human SOCS-3 (N-terminal) protein fragments expressed in E.coli. |
| 计算分子量 | 25KD |
| 成分 | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH7.4,150mM NaCl) with 0.2% sodium azide,50% glycerol. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | SOCS3 (Suppressor of cytokine signaling 3) is a protein that in humans is encoded by the SOCS3 gene.SOCS3 is transiently expressed by multiple cell lineages within the immune system and functions predominantly as a negative regulator of cytokines that activate the JAK-STAT3 pathway.This gene encodes a member of the STAT-induced STAT inhibitor (SSI),also known as suppressor of cytokine signaling (SOCS),family.SSI family members are cytokine-inducible negative regulators of cytokine signaling.The expression of this gene is induced by various cytokines,including IL6,IL10,and interferon (IFN)-gamma.The protein encoded by this gene can bind to JAK2 kinase,and inhibit the activity of JAK2 kinase.For signaling of IL-6,Epo,GCSF and Leptin,binding of SOCS3 to the respective cytokine receptor has been found to be crucial for the inhibitory function of SOCS3.Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis,and placental development. |
| Uniprot ID | O14543 |
| 基因名全称 | Suppressor of cytokine signaling 3 |
| 蛋白名全称 | Suppressor of cytokine signaling 3 |
| 推荐稀释比 | WB 1:1000～1:2000 IHC 1:500～1:1000 |
相关搜索：SOCS3抗体，SOCS3单抗，Anti-SOCS3 Antibody